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KMID : 0665220090220020308
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Korean Journal of Food and Nutrition
2009 Volume.22 No. 2 p.308 ~ p.312
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Antineoplastic Effect of Low Molecular Weight Chitooligosaccharide on Various Tumor Cell Lines
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Park Heon-Kuk
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Abstract
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In this study, the effects of low molecular weight chitooligosaccharides were assessed. Low molecular weight chitooligosaccharide evidenced no cytotoxicity in in vitro trials with the normal cell line, Vero E6(Africa green monkey kidney cell). The of low molecular weight chitooligosaccharide was . Low molecular weight chitooligosaccharide exhibited in vitro antineoplastic activity in five human tumor(lung carcinoma, bladder carcinoma, colon carcinoma, stomach carcinoma, breast carcinoma) cell lines. The values of low molecular weight chitooligosaccharide on A549, J82, SNU-C4, SNU-1 and ZR75-1 were , , , , and , respectively.
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KEYWORD
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low molecular weight chitooligosaccharide, cytotoxicity, antineoplastic effect
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